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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CASS4
All Species:
12.12
Human Site:
S434
Identified Species:
26.67
UniProt:
Q9NQ75
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQ75
NP_001157588.1
786
87144
S434
E
E
S
A
K
E
L
S
L
D
L
D
V
A
K
Chimpanzee
Pan troglodytes
XP_001169779
786
87081
S434
E
E
S
A
K
E
L
S
L
D
L
D
V
A
K
Rhesus Macaque
Macaca mulatta
XP_001090515
786
86837
S434
E
E
S
A
K
E
L
S
L
D
L
D
V
A
K
Dog
Lupus familis
XP_534461
746
82524
R416
E
A
N
L
G
A
I
R
T
A
A
H
R
V
E
Cat
Felis silvestris
Mouse
Mus musculus
Q08EC4
804
88602
W432
E
D
S
V
K
E
L
W
M
D
V
D
F
A
K
Rat
Rattus norvegicus
Q63767
968
104244
A557
E
P
L
E
L
E
V
A
V
E
T
L
A
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509857
821
90320
A464
P
E
D
Q
E
A
A
A
L
D
L
E
L
A
K
Chicken
Gallus gallus
XP_417499
814
90427
K456
D
E
P
D
K
E
I
K
L
D
L
E
V
A
I
Frog
Xenopus laevis
NP_001084484
853
95724
T445
E
V
S
I
K
Q
E
T
L
E
L
D
E
A
I
Zebra Danio
Brachydanio rerio
XP_001341038
774
86396
V441
V
P
K
L
M
L
F
V
S
S
Q
W
R
S
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782316
831
91548
N431
E
T
L
G
R
R
L
N
L
D
R
D
A
A
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.3
93.6
64.2
N.A.
61
22.3
N.A.
51.4
43.4
38.5
29
N.A.
N.A.
N.A.
N.A.
23.8
Protein Similarity:
100
98.8
96
72.3
N.A.
71.5
38
N.A.
66.8
60.5
55.6
45.2
N.A.
N.A.
N.A.
N.A.
39.7
P-Site Identity:
100
100
100
6.6
N.A.
60
13.3
N.A.
40
53.3
46.6
0
N.A.
N.A.
N.A.
N.A.
40
P-Site Similarity:
100
100
100
26.6
N.A.
80
40
N.A.
66.6
73.3
66.6
13.3
N.A.
N.A.
N.A.
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
28
0
19
10
19
0
10
10
0
19
73
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
10
10
10
0
0
0
0
0
64
0
55
0
0
0
% D
% Glu:
73
46
0
10
10
55
10
0
0
19
0
19
10
0
10
% E
% Phe:
0
0
0
0
0
0
10
0
0
0
0
0
10
0
0
% F
% Gly:
0
0
0
10
10
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% H
% Ile:
0
0
0
10
0
0
19
0
0
0
0
0
0
0
19
% I
% Lys:
0
0
10
0
55
0
0
10
0
0
0
0
0
0
46
% K
% Leu:
0
0
19
19
10
10
46
0
64
0
55
10
10
0
10
% L
% Met:
0
0
0
0
10
0
0
0
10
0
0
0
0
0
10
% M
% Asn:
0
0
10
0
0
0
0
10
0
0
0
0
0
0
0
% N
% Pro:
10
19
10
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
10
0
10
0
0
0
0
10
0
0
0
0
% Q
% Arg:
0
0
0
0
10
10
0
10
0
0
10
0
19
10
10
% R
% Ser:
0
0
46
0
0
0
0
28
10
10
0
0
0
10
0
% S
% Thr:
0
10
0
0
0
0
0
10
10
0
10
0
0
0
0
% T
% Val:
10
10
0
10
0
0
10
10
10
0
10
0
37
10
0
% V
% Trp:
0
0
0
0
0
0
0
10
0
0
0
10
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _